Description
SSU72 is a highlyconserved homologue of yeast Ssu72, a CTD phosphatase and a component of thepolyadenylation/ termination machinery. Existing as multiple alternativelyspliced isoforms, SSU72 interacts with TFIIB, Rb and DNAM-1 and functions tocatalyze the dephosphorylation of target proteins, possibly playing a role inRNA processing and termination via dephosphorylation of Pol II